Interleukin-17: Friend or foe in organ fibrosis
نویسندگان
چکیده
منابع مشابه
IL-17 in lung disease: friend or foe?
Interleukin 17 (IL-17) is a key proinflammatory cytokine in the T helper 17 pathway. While it is important in the clearance of certain pathogens, IL-17 has been shown to contribute to the pathogenesis of such inflammatory diseases as rheumatoid arthritis and psoriasis. In the lung, it has been postulated to be involved in the neutrophilic inflammation and airway remodelling of chronic respirato...
متن کاملLinoleic acid supplement in cystic fibrosis: friend or foe?
SEVERAL CLINICAL OBSERVATIONS suggest that changes in a fatty acid concentration are associated with the pathogenesis of chronic lung disease. As an example, cystic fibrosis (CF) subjects have lower concentrations of essential fatty acids in their plasma lipids compared with normal control subjects (6, 7). Although pathogenesis of CF lung disease is not a direct consequence of changes in fatty ...
متن کاملAntioxidants - friend or foe?
Particularly in the field of advertising and in popular scientific journals, antioxidants such as β-carotene (from carrots) or lycopenes (from tomatoes) and the vitamins C and E are one-sidedly portrayed as substances capable of offering protection against cancer or ageing because they diminish or prevent the effects of free radicals. However, free radicals should by nomeans be considered as be...
متن کاملFriend or foe
For many years, β-defensins were best known for their antimicrobial activity. However, β-defensins also exert immunomodulatory functions, such as the chemotactic recruitment of immune cells via chemokine receptors. We demonstrated that mouse β-defensin 14 recruits CCR6(+) B cells into fibrosarcomas, resulting in enhanced angiogenesis and tumor development.
متن کاملNanofibers: Friend or Foe?
Alke Petri-Fink 1, Barbara Rothen-Rutishauser 1 and Martin J. D. Clift 1,2,* 1 BioNanomaterials, Adolphe Merkle Institute, University of Fribourg, Rte de l’Ancienne Papeterie, Marly 1, 1723 Fribourg, Switzerland; [email protected] (A.P.-F.); [email protected] (B.R.-R.) 2 Swansea University Medical School, Singleton Park Campus, Swansea University, Swansea, Wales SA2 8PP, UK * Corresponde...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Cytokine
سال: 2019
ISSN: 1043-4666
DOI: 10.1016/j.cyto.2018.11.003